Zerophilia

In this sexually ambiguous romantic comedy, Luke, a naive college student, struggles with issues of masculinity while he comes to terms with a rare genetic disorder that causes the afflicted to switch gender at will.

Zerophilia is a 2006 romance comedy movie directed by Martin Curland, starring Alison Folland, Taylor Handley, Kyle Schmid. It holds an IMDb rating of 6.1/10 from 2,548 votes and runs 1h 30m.