Habitat

In a future world where Earth's ozone layer has been completely destroyed, a brilliant but obsessed scientist, Hank Symes uses illegally obtained biological materials for an experiment that he hopes will save the world. In the course of his work, a terrible accident occurs, transforming him into a fantastic otherworldly lifeform and changing his house into a huge living entity which threatens all who enter.

Habitat is a 1997 sci-fi movie directed by Rene Daalder, starring Alice Krige, Balthazar Getty, Tchéky Karyo. It holds an IMDb rating of 4.7/10 from 1,036 votes and runs 2h .